Department of Pharmaceutics

Overview


Pharmaceutics is a core part of pharmacy course that deals with the process of turning a new chemical entity (NCE) into a medication to be used safely and effectively by patients. It also related to the Manufacturing, formulation, storage, Distribution, preservation, stability, utilization and pharmacokinetics of drug products and dispending of dosage forms or pharmaceutical. It is also called the science of dosage form design as it is study and design of drug formulation for optimum delivery, stability, pharmacokinetics, and patient acceptance.
Day by day many chemicals are synthesized with pharmacological properties, but need special measures to help them achieve therapeutically relevant amounts at their sites of action. Pharmaceutics helps relate the formulation of drugs to their delivery and disposition in the body.
This branch deals with the formulation of a pure drug substance into a dosage form. The preformulation studies leads to unit-operations and the chemical moiety is further designed into various compounding products, extemporaneous preparations and formulations leading to Novel drug delivery systems such as nanotechnology based delivery systems and biotechnology based drug delivery systems, transdermal patches, microspheres, Nano particles, liposomes etc. The stability testing of products, microbiological testing for bacterial, virus and fungus are also done. The various pharmacokinetic and pharmacodynamic aspects of the dosage form are determined to conclude on the dosage regimen. It also includes Drug Regulatory affairs which assures proper manufacturing, packing, sale and distribution of the drug through the licensed authority only.

Research Area for Pharmaceutics Department

  • SEDDS
  • Floating Drug Delivery System
  • Matrix release Drug Delivery System
  • Solubility Enhancement

Equipment Available in Department:

  • Spray Dryer –Lab Ultima

Stability Chamber-Thermolab

  • Tablet Compression Machine-
  • Kalweka Main Drive Unit with attachment
  • Dry granulator
  • Powder mixer
  • Homogeniser
  • Pelletizer Type
  • Planetory mixer
  • Wet granulator
  • Tablet dissolution tester model TDT-08L-Electrolab
  • Pan coating machine
  • Tap/Bulk Density apparatus
  • Brookfield Viscometer
  • Horizontal Laminar Airflow
  • Incubator
  • Sieve Shaker
  • Sterling testing unit
  • Antibiotic zone reader
  • BOD incubator

Department of Pharmaceutical Chemistry

Overview


Pharmaceutical chemistry is the study of drugs, and it involves drug development. This includes drug discovery, delivery, absorption, metabolism, and more. There are essentials of biomedical analysis, pharmacology, pharmacokinetics, and pharmacodynamics. Pharmaceutical chemistry involves cures and remedies for disease, analytical techniques, pharmacology, metabolism, and drug chemistry. Pharmaceutical chemistry leads to careers in drug development, biotechnology, pharmaceutical companies, research facilities, and more.Studying pharmaceutical chemistry allows students to contribute to life-saving remedies, enhance the speed of delivery of new medications, and help others. The department of pharmaceutical chemistry is concerned with conducting lectures in the subjects of organic chemistry, inorganic chemistry, pharmaceutical biochemistry, medicinal chemistry and pharmaceutical analysis for the undergraduate students in the four year B. Pharm. programme.
The department is well prepared to initiate these fundamental subjects to the students so that a strong base is laid at the very beginning. This foundation serves as the building block for all other subjects in the entire B. Pharm programme.
The department is involved in training pharmaceutical analysis to the undergraduates. The syllabus includes wide lectures and laboratory sessions to make certain that students can connect theory to practice and apply their theoretical understanding gained. The field of pharmaceutical analysis is very dynamic and the curriculum ensures that the students are remained side by side with the latest advance in this field. They are taught classical and modern analytical techniques including the application of sophisticated instruments like GC, HPLC, NMR, GC-MS, LC-MS etc. for drugs, pharmaceuticals and others.

The department has a postgraduate programme, M. Pharm. The students are actively engaged in research activities under faculty guidance in varied research projects like-

  • analytical method development and validation of APIs and formulations,
  • standardization of herbal products using modern analytical techniques,
  • phytochemistry, natural product isolation from plants and their bioactivity,
  • development and synthesis of anticancer and anti-infective.

The department has successfully organized many workshops as part of the “Quality improvement” series in the field of organic chemistry and pharmaceutical analysis for the teachers in pharmacy colleges. The department strives towards publishing their research in good impact factor journals and also attends and presents their research work in many national and international forum i.e conferences and seminars. The department is actively involved in writing research projects and has received research project grants from CDRI, Savitribai Phule Pune University

Department of Pharmacology

Overview


During the first year student must know about Biochemical parameters and Hematological parameters at SMBT COP we are conducting practicals of RBC WBC DLC estimation as well as Arneth index. During Third and Final year B. Pharm. students get thorough knowledge of lab animals also get trained for handling of animals. Different bioassays carried out by using isolated tissues. Two experienced faculty members engaged to upgrade the practical and theoretical knowledge of students. Both faculty members registered for Ph. D. from well known Universities

Instruments available

  • Plethysmometer
  • Eddy’s hot plate analgesiometer
  • Rota rod apparatus
  • Pole climbing apparatus
  • Actophotometer

Department of Pharmacognosy

Overview


Pharmacognosy is the study of the physical, chemical, biochemical and biological properties of drugs natural origin and also search for new drugs from natural sources. The study of crude drugs from plants includes the subjects of botany, chemistry and pharmacology.
Botany includes the identification (taxonomy), genetics, and cultivation of plants.
Chemical characterization of includes the isolation, identification and quantification of constituents in plant materials. Pharmacology is the study of the biological effects that the chemicals in medicinal plants have on cell cultures, animals and humans.

In the Department of Pharmacognosy, we conducted experiments on morphology, microscopy and physicochemical characteristics of crude drugs. Department of Pharmacognosy is fully devoted to provide quality education and research through natural products chemistry by exploring the local natural resources as remedies for management of endemic diseases. Department also engaged in extraction, isolation of phytoconstituents, herbal formulation development, evaluation, and standardization of crude drugs and Phytopharmaceuticals.

Department also has Medicinal plant garden. Department is having a major priority of planting trees in area provides for Medicinal plant cultivation (about 0.30 acre). The department also has Plant museum consist of history of pharmacognosy, charts of crude drug and specimen of herbariums.